Poneratoxin, a potent neurotoxin, is a peptide consisting of 20 amino acids found in the venom of the tropical marine cone snail, Conus ponderosus. It selectively targets and blocks voltage-gated sodium channels in nerve cells, disrupting nerve cell signaling and causing paralysis or even death in the cone snail's prey. Poneratoxin has shown potential therapeutic applications in chronic pain treatment, with demonstrated analgesic effects in animal models. However, its extreme potency and potential toxicity require further research to understand its mechanism of action and explore its medical applications.
137084-94-7
Post Buying Request-
-
Basic information
- Product Name: poneratoxin
- Synonyms: poneratoxin
- CAS NO:137084-94-7
- Molecular Formula: C129H215 N33 O31 S
- Molecular Weight: 2756.35
- EINECS: N/A
- Product Categories: N/A
- Mol File: 137084-94-7.mol
-
Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: poneratoxin(CAS DataBase Reference)
- NIST Chemistry Reference: poneratoxin(137084-94-7)
- EPA Substance Registry System: poneratoxin(137084-94-7)
-
Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 137084-94-7(Hazardous Substances Data)
137084-94-7 Suppliers
Recommended suppliersmore
137084-94-7 Usage
Uses
Used in Pharmaceutical Industry:Poneratoxin is used as a research tool for studying the function and mechanism of voltage-gated sodium channels in nerve cells. Its ability to selectively block these channels provides valuable insights into the development of drugs targeting specific ion channels for various neurological disorders.
Used in Pain Management Applications:
Poneratoxin is used as a potential therapeutic agent for the treatment of chronic pain. Its analgesic effects in animal models have shown promise, but further research is needed to understand its mechanism of action and evaluate its safety and efficacy in clinical settings.
Used in Drug Development:
Poneratoxin serves as a lead compound in the development of new drugs targeting voltage-gated sodium channels. Its selective action on these channels can guide the design of more specific and potent pain relief medications with fewer side effects.
Used in Neurological Research:
Poneratoxin is used as a research tool in understanding the role of voltage-gated sodium channels in various neurological conditions, such as epilepsy, neuropathic pain, and multiple sclerosis. Its ability to block these channels can help researchers explore the potential of targeting these channels for therapeutic intervention in these diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 137084-94-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,7,0,8 and 4 respectively; the second part has 2 digits, 9 and 4 respectively.Calculate Digit Verification of CAS Registry Number 137084-94:
(8*1)+(7*3)+(6*7)+(5*0)+(4*8)+(3*4)+(2*9)+(1*4)=137
137 % 10 = 7
So 137084-94-7 is a valid CAS Registry Number.
137084-94-7Upstream product
137084-94-7Downstream Products
Post a RFQ
1
What can I do for you?
Get Best Price
Get Best Price for 137084-94-7
poneratoxin
