137105-53-4Relevant academic research and scientific papers
Rotenoid Synthesis by Wadsworth-Emmons Coupling and Mukaiyama Cyclisation: Application to 5-Thiorotenoids
crombie, Leslie,Josephs, Jonathan L.
, p. 2599 - 2604 (2007/10/02)
A new synthesis of general applicability to rotenoid structures is described, through its specific objectives were 5-thiorotenoids.The synthons carrying the A/B- and the B/C-ring components are coupled by Wadsworth-Emmons synthesis and the ring B chromene is formed by Mukaiyama directed aldol cylisation: Michael addition completes the formation of the rotenoid at its correct oxidation state and in its stable cis-form.Examples with, and without 2,3-dimethoxylation in ring A are described.
5-Thiorotenoids: A New Synthesis of General Applicability to Rotenoids
Crombie, Leslie,Josephs, Jonathan L.,Larkin, John,Weston, John B.
, p. 972 - 973 (2007/10/02)
A new synthesis of general utility for rotenoid structures is reported and applied to the specific case of 5-thiorotenoids.
