137121-69-8

Upstream product

• 107798-93-6 1-Benzyl-4-phenylurazole 
• 542-92-7 cyclopenta-1,3-diene 
• 98186-09-5 2-(4-Phenylurazolyl)cyclohexanone 
• 67818-00-2 (Z)-2-(3,5-Dioxo-4-phenyl-[1,2,4]triazolidin-1-yl)-3-hydroxy-but-2-enoic acid ethyl ester 
• 4233-33-4 4-Phenyl-1,2,4-triazolidine-3,5-dione 
• 83953-54-2 2-azanorbornadiene 
• 34822-90-7 cyclopentadienylthallium 
• 5164-35-2 bicyclo[2.1.0]pent-2-ene 

Downstream Products

• 10316-52-6 2-phenyl-tetrahydro-5,8-methano-[1,2,4]triazolo[1,2-a]pyridazine-1,3-dione 
• 195197-65-0 (1R,7S,8R,9S)-8,9-Dihydroxy-4-phenyl-2,4,6-triaza-tricyclo[5.2.1.0^2,6]decane-3,5-dione 
• 195197-72-9 N-((1R,2S,3R,4S)-2,3-Dihydroxy-4-phenylacetylamino-cyclopentyl)-2-phenyl-acetamide 

Relevant academic research and scientific papers

Anodic co-oxidation of urazole and ferrocenes: First trapping of cyclopentadienols

Cyclopentadien-5-ols, the major products resulting from decomposition of some ferrocenium cations by molecular oxygen, are regio- and stereo-selectively trapped by 4-phenyl-1,2,4-triazoline-3,5-dione.

Biocatalysis in the chiral recognition of meso-diamides - An efficient route from cyclic olefinic hydrocarbons to optically pure diamino-polyols

meso-Diamino-di(tri,tetr)ols 1-8 were synthesized starting from cheap carbocyclic olefins and cis-diepoxy derivatives. Enantioselective hydrolysis of the corresponding bis(phenylacet)amides with penicillin amidase from E. coli (EC 3.5.1.11) was effected in good yields (73-90%) and with high optical purities (ee 91 - >97).

5-Fluorocyclopentadiene: Synthesis and Utility

5-Fluorocyclopentadiene 2 has been prepared by the reaction of cyclopentadienylthallium and the F(+) source, 1-chloromethyl-4-fluoro-1,4-diazoniabicyclooctane bis(tetrafluoroborate).In their reactions with compound 2, dienophiles form adducts having exclusively syn orientation.

An Improved Synthesis of 1α-hydroxy Vitamin D3

The efficient and stereoselective introduction of the 1α-OH function in vitamin D3 is described starting from the known previtamin D3 adduct 6.The sequence involves the stereoselective allylic bromination to 9, followed by substituti

2-azanorbornadiene

The unstable and hitherto unknown 2-azanorbornadiene 1, interesting example of imine-olefin homoconjugation, has been generated and spectroscopically characterized. Its instability is due to a retro-Diels-Alder reaction which generates cyclopentadiene and hydrogen cyanide.

Synthesis and Chemistry of Acyltriazolinedione Ylides and Related Intermediates: New Methods for the Preparation of Di- and Tricarbonyl Compounds

α-Urazolylcarbonyl compounds can be easily oxidized to the corresponding ylides, and these ylides hydrolyzed to the corresponding carbonyl compounds.In addition these same urazole precursors can be converted to carbonyl compounds via a novel version of the Swern oxidation.These two methods not only are of synthetic value in the preparation of 1,2-dicarbonyl and 1,2,3-tricarbonyl compounds but also serve as useful probes for the formation of triazolinedione ylides and the related urazolium species.

Carbon Acidity. 68. Hydrogen Isotope Exchange Kinetics of 1,3-Diphenylindene, Cyclopentadiene, 1,4-Diphenylcyclopentadiene, and 2,7-Di-tert-butylfluorene

Second-order rate constants for the hydrogen isotope exchange reactions of 1,3-diphenylindene, cyclopentadiene, 1,4-diphenylcyclopentadiene, and 2,7-di-tert-butylfluorene in methanolic sodium methoxide are reported, and these data are compared with the co

DIENOPHILIC AND DIPOLAR ADDITIONS TO BICYCLOPENT-2-ENE

The dienophiles triazolinedione, singlet oxygen and in part tetracyanoethylene cycloadd to bicyclopent-2-ene (1) across the central ?-bond to give bicycloheptene-type adducts, while the dipoles phenyl azide, benzonitrile oxide and diphenyldiazomethane cycloadd at the ?-bond with expected exo stereochemistry.