137128-79-1Relevant academic research and scientific papers
Propiophenone derivatives and their preparation and pharmaceutical use
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, (2008/06/13)
The present invention relates to compounds represented by the general formula I in which X1, X2represent hydrogen, C1 4-alky phenyl, halogen, C1 4-alkoxy or dialkylamino with C1 4-alkyl groups, or X1 and X2 together represent phenylene or indane-2,3-diyl, Z1, Z2represent hydrogen or hydroxy, or together represent oxygen or -O(CH2)2O-, Y1, Y2represent hydrogen, C1 3-alkyl or phenyl, Arepresents a group derived from a cyclic amine,and nrepresents 0, 1 or 2, in the form of the free base or in the form of addition salts, preferably pharmaceutically acceptable salts, to methods for their preparation, and to their pharmaceutical use as central muscle relaxants and anticonvulsives.
