137159-92-3 Usage
Uses
Used in Pharmaceutical Industry:
APTIGANEL HYDROCHLORIDE is used as a therapeutic agent for the treatment of stroke and traumatic brain injury. Its application is based on its ability to block NMDA ion channels, which can help prevent the overstimulation of these receptors and reduce the severity of the damage caused by these conditions.
Used in Neurological Treatment:
APTIGANEL HYDROCHLORIDE is used as a neuroprotective agent to mitigate the effects of neurological disorders associated with excessive NMDA receptor activity. By blocking these receptors, it can potentially reduce the extent of brain damage and improve patient outcomes.
Brand Name:
The brand name for APTIGANEL HYDROCHLORIDE is Cerestat, which is manufactured by Cambridge Laboratories.
Check Digit Verification of cas no
The CAS Registry Mumber 137159-92-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,7,1,5 and 9 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 137159-92:
(8*1)+(7*3)+(6*7)+(5*1)+(4*5)+(3*9)+(2*9)+(1*2)=143
143 % 10 = 3
So 137159-92-3 is a valid CAS Registry Number.
InChI:InChI=1/C20H21N3/c1-3-15-8-6-11-17(14-15)23(2)20(21)22-19-13-7-10-16-9-4-5-12-18(16)19/h4-14H,3H2,1-2H3,(H2,21,22)
137159-92-3Relevant academic research and scientific papers
TRI- AND TETRA-SUBSTITUTED GUANIDINES AND THEIR USE AS EXCITATORY AMINO ACID ANTAGONISTS
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, (2008/06/13)
Tri-and tetra-substituted guanidines which exhibit a high binding affinity to phencyclidine (PCP) receptors and, more preferably, low affinity to the brain sigma receptors. These guanidine derivatives act as non-competitive inhibitorsSTATEMENT AS TO RIGHT
