1371592-07-2

Upstream product

• 77801-60-6 4-chloro-1-benzyl-1H-indole 
• 1371591-91-1 1-benzyl-4-chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-indole 
• 209223-84-7 1-(2′-bromophenyl)-2-methylpropan-1-one 
• 1371591-88-6 1-benzyl-4-chloro-3-iodoindole 
• 25235-85-2 4-chloro-1H-indole 

Downstream Products

• 1371592-16-3 2-benzyl-6,6-dimethyl-2,6-dihydro-2-aza-dibenzo[cd,h]azulen-7-one 

Relevant academic research and scientific papers

Synthesis of tetracyclic indoles via intramolecular α-arylation of ketones

Figure Persented: An intramolecular palladium(0)-mediated α-arylation of ketones applied to the synthesis of various substituted tetracyclic indoles is reported. Most significantly, the efficiency of the transformation was enhanced by the use of monoligated Pd(0) complexes. This methodology was extended to double α-arylation of ketones using one-pot reactions with either simultaneous addition or sequential addition of two aryl halides for producing aryl substituted tetracyclic indoles.