137160-70-4Relevant academic research and scientific papers
Useful four-carbon synthons en route to monastrol analogs
Abdou, Amr M.,Botros,Hassan, Rasha A.,Kamel, Mona M.,Taber, Douglass F.,Taher, Azza T.
, p. 139 - 146 (2015/02/18)
A simple protocol has been established for the preparation of a family of crystalline N-aryl γ-hydroxycrotonamides, useful four-carbon synthons. These were further elaborated to analogs of monastrol having variant ester sidechains, that were evaluated for their anticancer activity employing the NCI 60 cell line panel.
Zinc mediated facile amide formation : Application to alkyl, aryl, heterocycle, carbohydrate and amino acids
Meshram,Reddy, Gondi Sudershan,Reddy, M. Muralidhar,Yadav
, p. 4103 - 4106 (2007/10/03)
Synthesis of alkyl, aryl, heterocyclic, carbohydrate and amino acid amides using activated zinc is described. The recovery and reuse of the zinc makes the procedure more economic.
Oxime esters as acylating agents in the aminolysis reaction. A simple and chemoselective method for the preparation of amides from amino alcohols
Fernandez,Menendez,Gotor
, p. 713 - 716 (2007/10/02)
Oxime esters, such as acetone O-alkanoyl-, O-alkenoyl- or O-benzyloxycarbonyloximes, react with amines under extremely mild conditions to give the corresponding amides in very good yield. When amino alcohols are used a total chemoselectivity is observed.
