1371607-90-7Relevant academic research and scientific papers
Catalyst-free and highly selective electrophilic mono-fluorination of acetoacetamides: Facile and efficient preparation of 2-fluoroacetoacetamides in PEG-400
Bi, Jingjing,Zhang, Zhiguo,Liu, Qingfeng,Zhang, Guisheng
, p. 1159 - 1162 (2012)
Series of α-mono-fluorinated acetoacetamides were synthesized under mild condition with industrialized Selectfluor as the F+ source in PEG-400. The approach avoided the use of base or metal catalyst, and most of cases proceeded in nearly quanti
