1371638-05-9

Basic information

• Product Name: 1,2-Bis[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethane
• Synonyms: 1,2-Bis[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethane;1,2-bis(2-(4-(Dibenzo[b,f][1,4]thiazepin-11-yl)piperazin-1-yl)ethoxy)ethane tetrahydrochloride;Quetiapine EP Impurity E;Quetiapine Impurity 23;1,2-bis(2-(4-(dibenzo[b,f][1,4]thiazepin-11-yl)piperazin-1-yl)ethoxy)ethane
• CAS NO: 1371638-05-9
• Molecular Formula: C40H44N6O2S2
• Molecular Weight: 704.94636
• Product Categories: Impurities, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
• Mol File: 1371638-05-9.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: Dichloromethane (Slightly), Chloroform (Slightly), DMSO (Slightly)
• CAS DataBase Reference: 1,2-Bis[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethane(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-Bis[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethane(1371638-05-9)
• EPA Substance Registry System: 1,2-Bis[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethane(1371638-05-9)

Safety Data

• Hazardous Substances Data: 1371638-05-9(Hazardous Substances Data)

Usage

Description

1,2-Bis[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethane is a complex organic compound that is identified as an impurity in Quetiapine, an atypical antipsychotic medication. 1,2-Bis[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethane is characterized by its intricate molecular structure, which includes dibenzothiazepine and piperazine moieties, and is relevant in the pharmaceutical context due to its association with Quetiapine.

Uses

Used in Pharmaceutical Industry:
1,2-Bis[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethane is used as an impurity in the production of Quetiapine (Q510000), an atypical antipsychotic agent. It is crucial for the pharmaceutical industry to monitor and control the levels of this impurity to ensure the safety, efficacy, and quality of Quetiapine as a treatment for patients with schizophrenia, bipolar disorder, and major depressive disorder.
The presence of this impurity in Quetiapine highlights the importance of stringent quality control measures in the pharmaceutical manufacturing process. It is used as a reference point for assessing the purity of the active pharmaceutical ingredient and for developing methods to minimize or eliminate its presence in the final drug product. This contributes to the overall goal of providing safe and effective medications for the treatment of various mental health conditions.