1371641-80-3

Basic information

• Product Name: C₄₄H₆₀N₄O₉Si
• Synonyms: C₄₄H₆₀N₄O₉Si
• CAS NO: 1371641-80-3
• Molecular Weight: 817.067
• Mol File: 1371641-80-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₄₄H₆₀N₄O₉Si(CAS DataBase Reference)
• NIST Chemistry Reference: C₄₄H₆₀N₄O₉Si(1371641-80-3)
• EPA Substance Registry System: C₄₄H₆₀N₄O₉Si(1371641-80-3)

Safety Data

• Hazardous Substances Data: 1371641-80-3(Hazardous Substances Data)

Upstream product

• 1253799-71-1 ((4aS,8aS,9S)-3-(benzyloxy)-5-((tert-butyldimethylsilyl)oxy)-9-(dimethylamino)-4a-hydroxy-8a,9-dihydronaphtho[2,3-d]isoxazol-4(4aH)-one) 
• 1095276-65-5 C₂₁H₂₅NO₅ 
• 1371641-68-7 C₂₉H₄₁N₃O₅Si 

Relevant articles and documents

SYNTHESIS OF C5-SUBSTITUTED TETRACYCLINES, USES THEREOF, AND INTERMEDIATES THERETO

The tetracycline class of antibiotics has played a major role in the treatment of infectious diseases for the past 50 years. However, the increased use of the tetracyclines in human and veterinary medicine has led to resistance among many organisms previously susceptible to tetracycline antibiotics. The recent development of a modular synthesis of tetracycline analogs through a chiral enone intermediate has allowed for the efficient synthesis of novel tetracycline analogs never prepared before. The present invention provides more efficient routes for preparing the enone intermediate and allows for a wide variety of substituents at position 5 of the tetracycline ring system.