1371663-81-8

Upstream product

• 19021-53-5 methyl (2-methylbut-3-yn-2-yl)carbonate 
• 5446-02-6 4-methoxymethylsalicylate 

Downstream Products

• 1459804-81-9 (S)-methyl 2-(benzyloxy)-3-(2,3-dihydroxy-3-methylbutyl)-4-methoxybenzoate 
• 1459804-83-1 (R)-methyl 2-(benzyloxy)-3-((3,3-dimethyloxiran-2-yl)methyl)-4-methoxybenzoate 
• 1459804-79-5 methyl 2-(benzyloxy)-4-methoxy-3-(3-methylbut-2-en-1-yl)benzoate 
• 1459804-78-4 methyl 2-hydroxy-4-methoxy-3-(3-methylbut-2-en-1-yl)benzoate 
• 1459804-86-4 (R)-2-((3,3-dimethyloxiran-2-yl)methyl)-3,6-dimethoxyphenol 

Relevant academic research and scientific papers

The first asymmetric total synthesis of (+)-coriandrone A and B

The first enantioselective total synthesis of (+)-coriandrone A and B, two bioactive natural products, has been achieved in 10 steps and 11 steps starting from commercially available methyl 2-hydroxy-4-methoxybenzoate. Key reactions include a Claison rearrangement, a Shi-type epoxidation-cyclization sequence and ortho-metallation of t-butylbenzamides with (S)-(-)-propylene oxide reaction.