1,2-Dehydrobudesonide is an impurity found in the synthesis of Budesonide (B689490), which is a non-halogenated glucocorticoid related to triamcinolone hexacetonide. It plays a significant role in the pharmaceutical industry due to its association with Budesonide, a widely used anti-inflammatory agent.
137174-25-5
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Basic information
- Product Name: 1,2-Dehydrobudesonide
- Synonyms: Budesonide IMpurity G (1, 2-Dihydro Budesonide);1,2-Dihydrobudesonide;1,2-Dehydrobudesonide;Budesonide EP Impurity G;16α,17-[(1RS)-butylidenebis(oxy)]-11β,21-dihydroxypregn-4-ene-3,20-dione
- CAS NO:137174-25-5
- Molecular Formula: C25H36O6
- Molecular Weight: 432.54974
- EINECS: N/A
- Product Categories: Pharmaceuticals, Intermediates & Fine Chemicals, Steroids
- Mol File: 137174-25-5.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: 596.7±50.0 °C(Predicted)
- Flash Point: N/A
- Appearance: /
- Density: 1.26±0.1 g/cm3(Predicted)
- Refractive Index: N/A
- Storage Temp.: -20°C Freezer, Under inert atmosphere
- Solubility: Chloroform (Slightly), Dichloromethane (Slightly), Ethyl Acetate (Slightly, Heat
- PKA: 12.87±0.10(Predicted)
- CAS DataBase Reference: 1,2-Dehydrobudesonide(CAS DataBase Reference)
- NIST Chemistry Reference: 1,2-Dehydrobudesonide(137174-25-5)
- EPA Substance Registry System: 1,2-Dehydrobudesonide(137174-25-5)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 137174-25-5(Hazardous Substances Data)
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137174-25-5 Usage
Uses
Used in Pharmaceutical Industry:1,2-Dehydrobudesonide is used as an impurity in the synthesis of Budesonide for its anti-inflammatory properties. Budesonide is a potent corticosteroid that is commonly used to treat various inflammatory conditions, such as asthma, allergic rhinitis, and skin disorders. The presence of 1,2-Dehydrobudesonide in the synthesis process is crucial for the development and effectiveness of Budesonide as a medication.
Check Digit Verification of cas no
The CAS Registry Mumber 137174-25-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,7,1,7 and 4 respectively; the second part has 2 digits, 2 and 5 respectively.Calculate Digit Verification of CAS Registry Number 137174-25:
(8*1)+(7*3)+(6*7)+(5*1)+(4*7)+(3*4)+(2*2)+(1*5)=125
125 % 10 = 5
So 137174-25-5 is a valid CAS Registry Number.
137174-25-5 Well-known Company Product Price
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USP
(1078267) Budesonide Related Compound G United States Pharmacopeia (USP) Reference Standard
137174-25-5
1078267-25MG
14,500.98CNY
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1,2-Dehydrobudesonide
