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13721-39-6

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13721-39-6 Usage

Chemical Properties

white to off-white powder

Uses

Different sources of media describe the Uses of 13721-39-6 differently. You can refer to the following data:
1. Sodium orthovanadate is an alkaline phosphatase and (Na,K)-ATPase inhibitor with IC50 of 10 μM.
2. Sodium Orthovanadate is an inhibitor of several phosphatases and kinases. General inhibitor of tyrosine phosphatases, a large family of enzymes that catalyze the removal of phosphate groups from tyrosine residues.
3. Sodium orthovanadate (Na3VO4) can be used as a metal precursor in the synthesis of:Vanadium-MCM-48 (V-MCM-48) by anion-exchange method. V-MCM-48 is used as a catalyst in oxidation of styrene to benzaldehyde.Nanorods of vanadium oxide particles by glycothermal method.Yttrium vanadate (YVO4) doped with colloidal europium.

Biological Activity

Inhibitor of protein tyrosine phosphatases, alkaline phosphatases and ATPases.

Biochem/physiol Actions

Sodium orthovandate suppresses the activation of p53-mediated apoptosis triggered in response to radiation. It reduces the detrimental effects of hematopoietic syndrome, hematopoiesis and delayed genotoxic effects of induced by total body irradiation of mice.24 In combination with menadione, orthovandate prevents the migration of detached human glioma cells in response to anti-cancer drugs.25

Safety Profile

Poison by ingestion, intraperitoneal, intravenous, and subcutaneous routes. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of VOx and NazO. See also VANADIUM COMPOUNDS.

Check Digit Verification of cas no

The CAS Registry Mumber 13721-39-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,7,2 and 1 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 13721-39:
(7*1)+(6*3)+(5*7)+(4*2)+(3*1)+(2*3)+(1*9)=86
86 % 10 = 6
So 13721-39-6 is a valid CAS Registry Number.
InChI:InChI=1/3Na.4O.V/q3*+1;;;;;-3/r3Na.O4V/c;;;1-5(2,3)4/q3*+1;-3

13721-39-6 Well-known Company Product Price

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  • (Code)Product description
  • CAS number
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  • Detail
  • Alfa Aesar

  • (81104)  Sodium orthovanadate, 99.9% (metals basis)   

  • 13721-39-6

  • 25g

  • 755.0CNY

  • Detail
  • Alfa Aesar

  • (81104)  Sodium orthovanadate, 99.9% (metals basis)   

  • 13721-39-6

  • 100g

  • 2709.0CNY

  • Detail
  • Alfa Aesar

  • (81104)  Sodium orthovanadate, 99.9% (metals basis)   

  • 13721-39-6

  • 500g

  • 12210.0CNY

  • Detail
  • Sigma

  • (S6508)  Sodiumorthovanadate  ≥90% (titration)

  • 13721-39-6

  • S6508-10G

  • 362.70CNY

  • Detail
  • Sigma

  • (S6508)  Sodiumorthovanadate  ≥90% (titration)

  • 13721-39-6

  • S6508-50G

  • 1,244.88CNY

  • Detail
  • Sigma

  • (S6508)  Sodiumorthovanadate  ≥90% (titration)

  • 13721-39-6

  • S6508-250G

  • 4,998.24CNY

  • Detail
  • Aldrich

  • (450243)  Sodiumorthovanadate  99.98% trace metals basis

  • 13721-39-6

  • 450243-10G

  • 625.95CNY

  • Detail
  • Aldrich

  • (450243)  Sodiumorthovanadate  99.98% trace metals basis

  • 13721-39-6

  • 450243-50G

  • 2,472.21CNY

  • Detail

13721-39-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name Sodium orthovanadate

1.2 Other means of identification

Product number -
Other names Trisodium tetraoxovanadate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:13721-39-6 SDS

13721-39-6Upstream product

13721-39-6Downstream Products

13721-39-6Related news

Sodium orthovanadate (cas 13721-39-6) inhibits growth of human hepatocellular carcinoma cells in vitro and in an orthotopic model in vivo09/09/2019

The transition metal vanadium is widely distributed in the environment and exhibits various biological and physiological effects in the human body. As a well known vanadium compound, sodium orthovanadate (SOV) has shown promising antineoplastic activity in several human cancers. However, the eff...detailed

Research reportAttenuation of hyperhomocysteinemia induced vascular dementia by Sodium orthovanadate (cas 13721-39-6) perhaps via PTP1B: Pertinent downstream outcomes09/07/2019

Vascular dementia (VaD) is the second most common form of dementia after Alzheimer’s disease, but drug regulatory authorities have not approved any effective medication for this indication. Researchers are keenly aware of the need to uncover precise and druggable targets for VaD. However, findi...detailed

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