13721-39-6 Usage
Chemical Properties
white to off-white powder
Uses
Different sources of media describe the Uses of 13721-39-6 differently. You can refer to the following data:
1. Sodium orthovanadate is an alkaline phosphatase and (Na,K)-ATPase inhibitor with IC50 of 10 μM.
2. Sodium Orthovanadate is an inhibitor of several phosphatases and kinases. General inhibitor of tyrosine phosphatases, a large family of enzymes that catalyze the removal of phosphate groups from tyrosine residues.
3. Sodium orthovanadate (Na3VO4) can be used as a metal precursor in the synthesis of:Vanadium-MCM-48 (V-MCM-48) by anion-exchange method. V-MCM-48 is used as a catalyst in oxidation of styrene to benzaldehyde.Nanorods of vanadium oxide particles by glycothermal method.Yttrium vanadate (YVO4) doped with colloidal europium.
Biological Activity
Inhibitor of protein tyrosine phosphatases, alkaline phosphatases and ATPases.
Biochem/physiol Actions
Sodium orthovandate suppresses the activation of p53-mediated apoptosis triggered in response to radiation. It reduces the detrimental effects of hematopoietic syndrome, hematopoiesis and delayed genotoxic effects of induced by total body irradiation of mice.24 In combination with menadione, orthovandate prevents the migration of detached human glioma cells in response to anti-cancer drugs.25
Safety Profile
Poison by ingestion, intraperitoneal, intravenous, and subcutaneous routes. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of VOx and NazO. See also VANADIUM COMPOUNDS.
Check Digit Verification of cas no
The CAS Registry Mumber 13721-39-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,7,2 and 1 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 13721-39:
(7*1)+(6*3)+(5*7)+(4*2)+(3*1)+(2*3)+(1*9)=86
86 % 10 = 6
So 13721-39-6 is a valid CAS Registry Number.
InChI:InChI=1/3Na.4O.V/q3*+1;;;;;-3/r3Na.O4V/c;;;1-5(2,3)4/q3*+1;-3