1372155-66-2Relevant academic research and scientific papers
Cu-Catalyzed Regioselective C-H Alkylation of Benzimidazoles with Aromatic Alkenes
He, Yu-Ting,Mao, Yang-Jie,Hao, Hong-Yan,Xu, Zhen-Yuan,Lou, Shao-Jie,Xu, Dan-Qian
, p. 8250 - 8255 (2020)
Herein we report a novel Cu-catalyzed regioselective C2-H alkylation of benzimidazoles with aromatic alkenes. The reaction features exclusive regioselectivity and broad substrate scope in the intermolecular alkylation of benzimidazoles with terminal and i
The regioselective switch for amino-NHC mediated C-H activation of benzimidazole via Ni-Al synergistic catalysis
Shih, Wei-Chun,Chen, Wen-Ching,Lai, Ying-Chieh,Yu, Ming-Shiuan,Ho, Jhao-Jhe,Yap, Glenn P. A.,Ong, Tiow-Gan
supporting information; experimental part, p. 2046 - 2049 (2012/06/18)
We have disclosed a new mode of a chemically regioselective switch for C-H bond functionalization of benzimidazole derivatives via a cooperative effect invoked by Ni-Al bimetallic catalysis to create a steric requirement for obtaining the linear product of styrene insertion. Yet, excluding the AlMe 3 cocatalyst switches the reaction toward branch selectivity.
