137225-09-3 Usage
Uses
Used in Pharmaceutical Industry:
2-[(4-methoxyphenyl)amino]isonicotinonitrile is used as a chemical intermediate for the synthesis of various drugs and pharmaceutical products. Its unique structure and properties allow it to be a key component in the development of new medications.
Used in Organic Synthesis:
In the field of organic synthesis, 2-[(4-methoxyphenyl)amino]isonicotinonitrile is utilized as a building block for the creation of complex organic molecules, contributing to the advancement of chemical research and the discovery of new compounds with potential applications.
Used in Medicinal Chemistry:
2-[(4-methoxyphenyl)amino]isonicotinonitrile is employed as a valuable compound in medicinal chemistry for the exploration of its potential therapeutic effects. Its antimicrobial and antitumor activities are of particular interest, as they could lead to the development of new treatments for various diseases.
Used in Research and Development:
2-[(4-methoxyphenyl)amino]isonicotinonitrile is also used in research and development for further exploration of its pharmacological properties. The study of 2-[(4-methoxyphenyl)amino]isonicotinonitrile could uncover new insights into its potential as a therapeutic agent, leading to innovative approaches in drug discovery and treatment strategies.
Check Digit Verification of cas no
The CAS Registry Mumber 137225-09-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,7,2,2 and 5 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 137225-09:
(8*1)+(7*3)+(6*7)+(5*2)+(4*2)+(3*5)+(2*0)+(1*9)=113
113 % 10 = 3
So 137225-09-3 is a valid CAS Registry Number.
137225-09-3Relevant articles and documents
Efficient synthesis of 2-arylamino substituted pyridinyl nitriles by Buchwald-Hartwig amination
Guo, Shuo,Wang, Yaping,Sun, Chunxia,Li, Jingya,Zou, Dapeng,Wu, Yangjie,Wu, Yusheng
supporting information, p. 3233 - 3237 (2013/06/27)
Both nitrile and arylamino groups containing pyridine derivatives are synthesized from commercially available nitrile substituted pyridyl chlorides via a palladium-BINAP catalyst (the second generation catalyst for the amination) in moderate to good yields. The mild conditions permit the presence of base sensitive functional groups. Noteably, the halogen atoms linked to the aromatic ring were maintained in the structures of the products under the amination reaction conditions.
Photochemically Induced Electron Transfer from Aniline Derivatives to Pyridine-2,4-dicarbonitrile: Synthetic and Mechanistic Aspects
Bernardi, Rosanna,Caronna, Tullio,Morrocchi, Sergio,Vittimberga, Bruno M.
, p. 1411 - 1415 (2007/10/02)
A study on the photochemically induced electron transfer from substituted aniline donors to a 2,4-dicyanopyridine acceptor permits the synthesis of new amino derivatives of the pyridine and forms the basis of a hypothesis on the mechanism of the reaction and the influence of the substituent on the aniline ring.
