137233-58-0

Basic information

• Product Name: C₄₂H₇₁N₃O₁₄Si₂
• Synonyms: C₄₂H₇₁N₃O₁₄Si₂
• CAS NO: 137233-58-0
• Molecular Weight: 898.208
• Mol File: 137233-58-0.mol

Chemical Properties

• CAS DataBase Reference: C₄₂H₇₁N₃O₁₄Si₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₄₂H₇₁N₃O₁₄Si₂(137233-58-0)
• EPA Substance Registry System: C₄₂H₇₁N₃O₁₄Si₂(137233-58-0)

Safety Data

• Hazardous Substances Data: 137233-58-0(Hazardous Substances Data)

Upstream product

• 58-96-8 uridine 
• 81246-79-9 5'-dimethoxytrityluridine 
• 82444-76-6 2',3'-O-bis(tert-butyldimethylsilyl)-5'-O-(dimethoxytrityl)uridine 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 137233-56-8 methyl 2-(acetylamino)-4-O-benzoyl-6-deoxy-3-O-<(2-methoxyethoxy)methyl>-6-(phenylseleno)-α-D-galactopyranoside 
• 137233-57-9 2',3'-O-bis(tert-butyldimethylsilyl)-3-N-(p-methoxybenzyl)uridine 
• 137233-53-5 2',3'-O-bis(tert-butyldimethylsilyl)-3-N-(p-methoxybenzyl)uridine-5'-aldehyde 
• 137233-55-7 methyl 2-(acetylamino)-4-O-benzoyl-6-bromo-3-O-<(2-methoxyethoxy)methyl>-α-D-galactopyranoside 
• 137233-54-6 methyl 2-(acetylamino)-4,6-O-benzylidene-3-O-<(2-methoxyethoxy)methyl>-α-D-galactopyranoside 
• 137233-59-1 methyl 2-(acetylamino)-4-O-benzoyl-6-deoxy-5,6-didehydro-3-O-<(2-methoxyethoxy)methyl>-α-D-galactopyranoside 
• 137330-28-0 methyl 4,6-O-benzylidene-2-deoxy-2-acetamido-α-D-galactopyranoside 
• 137233-52-4 methyl 2-(acetylamino)-6-deoxy-5,6-didehydro-3-O-<(2-methoxyethoxy)methyl>-α-D-galactopyranoside 
• 137233-51-3 C₅₀H₇₉N₃O₁₄SeSi₃ 

Relevant articles and documents

Synthetic studies of the tunicamycin antibiotics. Preparation of (+)-tunicaminyluracil, (+)-tunicamycin-V, and 5′-epi-tunicamycin-V

A concise synthetic route to the tunicamycin antibiotics is described, illustrated by the preparation of (+)-tunicamycin-V (1-V). Key features of the synthesis include (1) the development and application of a silicon-mediated reductive coupling of aldehydes and allylic alcohols to construct the undecose core of the natural product and (2) the development of an efficient procedure for the synthesis of the trehalose glycosidic bond within the antibiotic. These innovations allow for the coupling of a uridine-derived aldehyde fragment with a performed trehalose-linked disaccharide allylic alcohol to form the carbohydrate core (1) of the natural product in a highly covergent manner. The resultant amino polyol is a versatile intermediate for the synthesis of any of the homologous tunicamycin antibiotics.