1372414-02-2

Basic information

• Product Name: 3,5-bis(4-nitrobenzyl)-1,2,4-thiadiazole
• Synonyms: 3,5-bis(4-nitrobenzyl)-1,2,4-thiadiazole
• CAS NO: 1372414-02-2
• Molecular Weight: 356.362
• Mol File: 1372414-02-2.mol

Chemical Properties

• CAS DataBase Reference: 3,5-bis(4-nitrobenzyl)-1,2,4-thiadiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-bis(4-nitrobenzyl)-1,2,4-thiadiazole(1372414-02-2)
• EPA Substance Registry System: 3,5-bis(4-nitrobenzyl)-1,2,4-thiadiazole(1372414-02-2)

Safety Data

• Hazardous Substances Data: 1372414-02-2(Hazardous Substances Data)

Upstream product

• 76254-70-1 2-(4-nitrophenyl)ethanethioamide 

Relevant articles and documents

Highly efficient oxidative dimerization of thioamides to 3,5-Disubstituted 1,2,4-thiadiazoles mediated by DDQ

A highly efficient oxidative dimerization of thioamides by 2,3-dichloro-5,6-dicyanobenzoquinone (DDQ) is reported. The reaction is carried out in ClCH2CH2Cl at room temperature. The corresponding 3,5-disubstituted 1,2,4-thiadiazoles are obtained in good to excellent yields.

Eosin y catalyzed visible-light-driven aerobic oxidative cyclization of thioamides to 1,2,4-thiadiazoles

A new approach for an efficient metal-free synthesis of 1,2,4-thiadiazoles from primary thioamides using visible light and air in the presence of eosin Y as a photoredox catalyst is reported. The protocol involves an aerobic oxidative cyclization of thioamides via the formation of C-N and C-S bonds to afford excellent yields of the products in a simple one-pot operation under mild conditions. Georg Thieme Verlag Stuttgart · New York.