1372452-60-2 Usage
Uses
Used in Ophthalmology:
(S)-3-(1-hydroxyethyl)benzenesulfonamide is used as an antiglaucoma agent for reducing intraocular pressure. By inhibiting carbonic anhydrase, it slows down the production of aqueous humor, which helps to decrease the risk of optic nerve damage and vision loss associated with glaucoma.
Used in Neurology:
In the field of neurology, (S)-3-(1-hydroxyethyl)benzenesulfonamide is used as an antiepileptic drug. It aids in controlling seizures by regulating the acid-base balance in the body, which can have a stabilizing effect on neuronal activity.
Used in Cardiology:
(S)-3-(1-hydroxyethyl)benzenesulfonamide is used as a diuretic in cardiology for treating conditions such as heart failure. Its diuretic effects help to reduce the buildup of excess fluid in the body, which can alleviate the strain on the heart and improve overall cardiovascular function.
Used in Urology:
In urology, (S)-3-(1-hydroxyethyl)benzenesulfonamide is used to treat kidney stones. Its diuretic properties facilitate the removal of calculi by increasing urine production and reducing the concentration of stone-forming substances in the urine.
Used in Sports Medicine:
(S)-3-(1-hydroxyethyl)benzenesulfonamide is used as an altitude sickness preventive in sports medicine. It helps to acclimate athletes and individuals to high-altitude environments by promoting the excretion of excess bicarbonate, which can prevent the symptoms of altitude sickness.
Check Digit Verification of cas no
The CAS Registry Mumber 1372452-60-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,7,2,4,5 and 2 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1372452-60:
(9*1)+(8*3)+(7*7)+(6*2)+(5*4)+(4*5)+(3*2)+(2*6)+(1*0)=152
152 % 10 = 2
So 1372452-60-2 is a valid CAS Registry Number.
1372452-60-2Relevant academic research and scientific papers
Preparative access to medicinal chemistry related chiral alcohols using carbonyl reductase technology
Rowan, Andrew S.,Moody, Thomas S.,Howard, Roger M.,Underwood, Toby J.,Miskelly, Iain R.,He, Yanan,Wang, Bo
, p. 1369 - 1381 (2013/12/04)
Libraries of highly enantioenriched secondary alcohols in both enantiomeric forms were synthesised by enzymatic reduction of their parent ketones using selectAZyme carbonyl reductase (CRED) technology. Commercially available CREDs were able to reduce a range of substrate classes efficiently and with very high enantioselectivity. Matching substrate classes to small subsets of CREDs enabled the fast development of preparative bioreductions and the rapid generation of 100-1500 mg samples of chiral alcohols in typically >95% ee and the majority in ≥99.0% ee. The conditions for small scale synthesis were then scaled up to 0.5 kg to deliver one of the chiral alcohols, (S)-1-(4-bromophenyl)-2-chloroethanol, in 99.8% ee and 91% isolated yield.
