1372719-98-6

Basic information

• Product Name: (1R)-2,2',3,3'-tetrahydro-6,6'-bis[2,4,6-tris(1-Methylethyl)phenyl]-1,1'-Spirobi[1H-indene]-7,7'-diol
• Synonyms: (1R)-2,2',3,3'-tetrahydro-6,6'-bis[2,4,6-tris(1-Methylethyl)phenyl]-1,1'-Spirobi[1H-indene]-7,7'-diol;(1R)-2,2',3,3'-Tetrahydro-6,6'-bis(2,4,6- trisisopropylphenyl)-1,1'-spirobi[1H-indene]-7,7'-diol;(R)-2,2',3,3'-Tetrahydro-6,6'-bis(2,4,6-trisisopropylphenyl)-1,1'-spirobi[1H-indene]-7,7'-diol
• CAS NO: 1372719-98-6
• Molecular Formula: C₄₇H₆₀O₂
• Molecular Weight: 656.9781
• Mol File: 1372719-98-6.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (1R)-2,2',3,3'-tetrahydro-6,6'-bis[2,4,6-tris(1-Methylethyl)phenyl]-1,1'-Spirobi[1H-indene]-7,7'-diol(CAS DataBase Reference)
• NIST Chemistry Reference: (1R)-2,2',3,3'-tetrahydro-6,6'-bis[2,4,6-tris(1-Methylethyl)phenyl]-1,1'-Spirobi[1H-indene]-7,7'-diol(1372719-98-6)
• EPA Substance Registry System: (1R)-2,2',3,3'-tetrahydro-6,6'-bis[2,4,6-tris(1-Methylethyl)phenyl]-1,1'-Spirobi[1H-indene]-7,7'-diol(1372719-98-6)

Safety Data

• Hazardous Substances Data: 1372719-98-6(Hazardous Substances Data)

Usage

General Description

(1R)-2,2',3,3'-tetrahydro-6,6'-bis[2,4,6-tris(1-Methylethyl)phenyl]-1,1'-Spirobi[1H-indene]-7,7'-diol, also known as Chiraphos, is a chiral ligand commonly used in organic synthesis and catalysis. It is a complex organic compound with a spirobiindane backbone and several phenyl groups substituted with isopropyl groups. Chiraphos is known for its ability to facilitate asymmetric catalysis in various chemical reactions, particularly in the formation of carbon-carbon and carbon-heteroatom bonds. Due to its unique structure and stereochemistry, Chiraphos has proven to be highly effective in promoting enantioselective transformations, making it a valuable tool in the field of modern synthetic chemistry.

Upstream product

• 1258276-29-7 (R)-6,6'-diiodo-7,7'-bis(methoxymethoxy)-2,2',3,3'-tetrahydro-1,1'-spirobiindane 
• 1258276-30-0 C₅₁H₆₈O₄ 
• 21524-34-5 2,4,6-triisopropyl-1-bromobenzene 

Downstream Products

• 1258276-28-6 (R)-6,6'-bis(2,4,6-triisopropylphenyl)-1,1'-spirobiindanyl-7,7'-diyl hydrogen phosphate 

Relevant articles and documents

Asymmetric allylboration of aldehydes with pinacol allylboronates catalyzed by 1,1′-spirobiindane-7,7′-diol (SPINOL) based phosphoric acids

The asymmetric allylboration of aldehydes with pinacolallylboronates catalyzed by 1,1′-spirobiindane-7,7′-diol (SPINOL) based phosphoric acids is described. 6,6′-Bis(2,4,6-triisopropylphenyl)SPINOL-based phosphoric acid was found to be a general, highly e