1372764-73-2

Basic information

• Product Name: C₄₇H₆₆N₂O₂
• CAS NO: 1372764-73-2
• Molecular Weight: 691.053
• Mol File: 1372764-73-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₄₇H₆₆N₂O₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₄₇H₆₆N₂O₂(1372764-73-2)
• EPA Substance Registry System: C₄₇H₆₆N₂O₂(1372764-73-2)

Safety Data

• Hazardous Substances Data: 1372764-73-2(Hazardous Substances Data)

Upstream product

• 1007345-49-4 3-oxolupan-28-oyl chloride 
• 841-77-0 diphenylmethylpiperazine 
• 7020-34-0 betulone 
• 97451-93-9 28-hydroxylupan-3-one 
• 25576-27-6 3-oxolupan-28-ic acid 

Relevant articles and documents

Antitumor activity of amides of dihydrobetulonic acid in vitro and in vivo

Amides containing homopiperidine and piperazine cycles were synthesized from dihydrobetulonic acid obtained by the oxidation of dihydrobetulin. All substances were shown to have a high antitumor activity (CCID50 = 3.5-36.2 μM) in vitro in lymphoid (CEM-13, U-937) and monocytic (MT-4) human cell lines. Amides containing the methyl- and ethylpiperazine residues do not influence the viability of Lung Lewis Carcinoma cells in culture and do not have a significant effect on its transplants in C57BL/6 mice. However, these amides efficiently inhibit the development of metastases in lungs of these mice. The antimetastatic activity of the studied amides increases with changing the methyl by ethyl aliphatic residue in the piperazine cycle.