1372797-64-2

Upstream product

• 34209-97-7 2,4-dichloro-1-(2-nitrovinyl)benzene 
• 123-54-6 acetylacetone 
• 18984-21-9 trans-2,4-dichloro-β-nitrostyrene 

Relevant academic research and scientific papers

Novel and highly efficient bifunctional calixarene thiourea derivatives as organocatalysts for enantioselective Michael reaction of nitroolefins with diketones

New bifunctional calixarene thiourea organocatalysts were synthesized and applied in catalytic asymmetric Michael addition of acetylacetone to various nitroolefins at room temperature. The corresponding adducts were obtained in good to excellent yields wi

Tertiary Amine-Derived Ionic Liquid-Supported Squaramide as a Recyclable Organocatalyst for Noncovalent "on Water" Catalysis

Chiral tertiary amine-derived ionic liquid-supported squaramide was synthesized from available precursors and applied as an efficient organocatalyst for asymmetric Michael additions of β-dicarbonyl compounds to α-nitroolefins in the presence of water. Cor

Calixarene-derived chiral tertiary amine-thiourea organocatalyzed asymmetric Michael additions of acetyl acetone and dimethyl malonate to nitroolefins

Novel bifunctional chiral thiourea-tertiary amines bearing a calix[4]arene scaffold were synthesized and applied in catalytic asymmetric Michael addition of acetyl acetone and dimethyl malonate to nitroolefins. The corresponding adducts were obtained in e

1,3-Diamine-Derived Bifunctional Organocatalyst Prepared from Camphor

Chiral 1,2-diamines are privileged structural motifs in organocatalysis, whereas efficient 1,3-diamine-derived organocatalysts are very rare. Herein we report a highly efficient camphor-1,3-diamine-derived squaramide organocatalyst. Its catalytic activity

Ferrocene as a scaffold for effective bifunctional amine-thiourea organocatalysts

A simple and readily accessible prototype of the ferrocene-based bifunctional amine-thioureas shows high enantioselectivity in the Michael addition of acetylacetone to nitroolefins, giving the enantioselectivity of up to 96% ee. This work demonstrates tha

Chiral squaramide-functionalized imidazolium-based organic-inorganic hybrid silica promotes asymmetric michael addition of 1,3-dicarbonyls to nitroalkenes in brine

Chiral cinchona-based squaramide-functionalized organic-inorganic hybrid silica is developed through postgrafting 3-mercaptopropyltrimethoxylsilane onto imidazolium-based organic-inorganic hybrid silica, followed by the anchor of a squaramide organocataly

Highly enantioselective Michael addition of 1,3-dicarbonyl compounds to nitroalkenes catalyzed by designer chiral BINOL-quinine-squaramide: Efficient access to optically active nitro-alkanes and their isoxazole derivatives

A chiral BINOL-quinine-squaramide has been identified as the best catalyst for the asymmetric Michael addition of nitroalkenes to 1,3-dicarbonyl compounds. A series of chiral nitroalkanes were prepared with approximately >99% ee. Furthermore, the methodol

Fast, solvent-free and hydrogen-bonding-mediated asymmetric Michael addition in a ball mill

The chiral squaramide derivatives as hydrogen bonding catalyst for the Michael addition reactions of 1,3-dicarbonyl compounds to nitroolefins under solvent-free conditions was developed using a planetary ball mill. High yields, high enantioselectivities a