1372809-53-4Relevant academic research and scientific papers
Acid-labile δ-ketal-β-hydroxy esters by asymmetric hydrogenation of corresponding δ-ketal-β-keto esters in the presence of CaCO 3
Fan, Weizheng,Li, Wanfang,Ma, Xin,Tao, Xiaoming,Li, Xiaoming,Yao, Ying,Xie, Xiaomin,Zhang, Zhaoguo
supporting information; experimental part, p. 4247 - 4249 (2012/05/05)
A series of acid-labile, optically pure ε-substituted δ-ketal-β-hydroxy esters were obtained by a Ru-SunPhos catalyzed asymmetric hydrogenation of the corresponding ε-substituted δ-ketal-β-keto esters. CaCO3 played a dual role in the hydrogenation reaction - removing the acid generated during the formation of the catalyst and maintaining the activity of the catalyst.
