1372858-48-4Relevant academic research and scientific papers
Identification of triazolopyridazinones as potent p38α inhibitors
Herberich, Brad,Jackson, Claire,Wurz, Ryan P.,Pettus, Liping H.,Sherman, Lisa,Liu, Qiurong,Henkle, Bradley,Saris, Christiaan J.M.,Wong, Lu Min,Chmait, Samer,Lee, Matthew R.,Mohr, Christopher,Hsieh, Faye,Tasker, Andrew S.
experimental part, p. 1226 - 1229 (2012/03/26)
Structure-activity relationship (SAR) investigations of a novel class of triazolopyridazinone p38α mitogen activated protein kinase (MAPK) inhibitors are disclosed. From these studies, increased in vitro potency was observed for 2,6-disubstituted phenyl m
