1372974-16-7Relevant academic research and scientific papers
Synthesis of pyrazolopyridine annulated heterocycles and study the effect of substituents on photophysical properties
Patil, Shivaraj P.,Shelar, Deepak P.,Toche, Raghunath B.
, p. 31 - 41 (2012)
Pyrazolo[3,4-b]pyridines having 4-chloro-5- chloroethyl side chain are synthesized by the reaction of 5-aminopyrazole and cyclic β-formylester gave aminopyrazolodihydrofuranone intermediate, which on cyclization in phosphorous oxychloride exclusively converted in to 4-chloro-5-chloroethyl pyrazolo[3,4-b]pyridines 4(a-b) in major amount. The side chain with acetic acid, thiourea and aromatic amines are used to form angular ring leads to formation of tricyclic Furo[2,3-d]pyrazolo[2,3-b]pyridines 5(a-b), pyrazolo[3,4-b]thieno[2,3-d]pyridines 6(a-b) and pyrazolo[3,4-b]pyrrolo[2,3-d] pyridines 7(a-n) respectively. The substituents effect at C4 position on fluorescence properties of pyrazolopyridines has been studied. Moreover the effect of electron donor and halogen substituents on fluorescence properties of pyrazolopyrrolopyridines 7(a-n) has been investigated along with their fluorescent quantum yield.
