137298-93-2

Upstream product

• 137298-91-0 tert-Butyl-{(E)-(1R,2S,4S,8R)-1-((1S,3R)-3-[1,3]dithian-2-yl-1-methoxy-butyl)-2-methoxy-8-[(2R,4R)-2-(4-methoxy-phenyl)-[1,3]dioxan-4-yl]-4,6-dimethyl-undeca-6,10-dienyloxy}-dimethyl-silane 
• 137298-89-6 (3S,5S,6R)-6-((1S,3R)-3-[1,3]Dithian-2-yl-1-methoxy-butyl)-5-methoxy-3-{(E)-(R)-4-[(2R,4R)-2-(4-methoxy-phenyl)-[1,3]dioxan-4-yl]-2-methyl-hepta-2,6-dienyl}-tetrahydro-pyran-2-one 
• 137298-90-9 (2S,4S,5R,6S,8R)-8-[1,3]Dithian-2-yl-4,6-dimethoxy-2-{(E)-(R)-4-[(2R,4R)-2-(4-methoxy-phenyl)-[1,3]dioxan-4-yl]-2-methyl-hepta-2,6-dienyl}-nonane-1,5-diol 
• 137298-88-5 (5S,6R)-6-((1S,3R)-3-[1,3]Dithian-2-yl-1-methoxy-butyl)-5-methoxy-tetrahydro-pyran-2-one 
• 128461-50-7 (5S,6R)-6-((1S,3R)-4-Benzyloxy-1-methoxy-3-methyl-butyl)-5-methoxy-tetrahydro-pyran-2-one 
• 137298-92-1 (E)-(3R,4R,8S,10S,11R,12S,14R)-4-Allyl-14-[1,3]dithian-2-yl-10,12-dimethoxy-3-(4-methoxy-benzyloxy)-6,8-dimethyl-11-triisopropylsilanyloxy-pentadec-5-en-1-ol 

Downstream Products

• 137298-85-2 (E)-(2R,3S,5R,6R,10S,12S,13R,14S,16R)-6-Allyl-16-[1,3]dithian-2-yl-12,14-dimethoxy-5-(4-methoxy-benzyloxy)-2,8,10-trimethyl-3,13-bis-triisopropylsilanyloxy-heptadec-7-enal 
• 137298-84-1 C₇₄H₁₃₈O₉S₂Si₃ 
• 137298-84-1 C₇₄H₁₃₈O₉S₂Si₃ 
• 137298-94-3 (4R,5S)-3-[(E)-(2R,3S,5R,6R,10S,12S,13R,14S,16R)-6-Allyl-16-[1,3]dithian-2-yl-3-hydroxy-12,14-dimethoxy-5-(4-methoxy-benzyloxy)-2,8,10-trimethyl-13-triisopropylsilanyloxy-heptadec-7-enoyl]-4-methyl-5-phenyl-oxazolidin-2-one 

Relevant academic research and scientific papers

Synthetic studies towards the immunosuppressant FK-506 synthesis of the C10-C34 fragment

The synthesis of the cyclohexyl moiety of FK-506 and its coupling reaction with the C10-C26 fragment to provide an advanced synthetic intermediate(C10-C34) are described.