1373010-34-4

Upstream product

• 50-00-0 formaldehyd 
• 1094173-00-8 (3S,5R)-1-(4-bromobenzyl)-3,5-dimethylpiperazine 
• 1373010-33-3 (2R,6S)-1-[(4-bromophenyl)methyl]-2,6-dimethylpiperazine 

Downstream Products

• 1373010-37-7 (2S,6R)-1,2,6-trimethyl-4-(4-((E)-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)vinyl)benzyl)piperazine 
• 1373010-85-5 (1R,2S)-2-(3-((E)-4-(((3S,5R)-3,4,5-trimethylpiperazin-1-yl)-methyl)styryl)-1H-indazol-6-yl)spiro[cyclopropane-1,3'-indolin]-2'-one 2,2,2-trifluoroacetate 

Relevant academic research and scientific papers

PLK-4 INHIBITORS AND METHOD OF TREATING CANCER WITH SAME

The invention is directed to a compound represented by the following Structural Formula (I) and (II) and pharmaceutically acceptable salts thereof: (Formula (I)); (Formula (IV)). Compounds represented by this structural formula are kinase inhibitors and are, therefore, disclosed herein for the treatment of cancer. Definitions for the variables in the structural formula are provided herein.