1373031-99-2

Upstream product

• 1373031-96-9 methyl 4-[(7-chloro-3,4-dihydro-1,1-dioxido-3-oxo-2H-1,2,4-benzothiadiazin-2-yl)methyl]benzoate 
• 1373031-98-1 4-[(7-chloro-3,4-dihydro-1,1-dioxido-3-oxo-2H-1,2,4-benzothiadiazin-2-yl)methyl]benzoic acid 
• 108-91-8 cyclohexylamine 
• 2417-72-3 Methyl 4-(bromomethyl)benzoate 
• 5800-59-9 7-chloro-2,3-dihydro-3-oxo-4H-1,2,4-benzothiadiazine 

Relevant academic research and scientific papers

Synthesis and evaluation of piperidine urea derivatives as efficacious 11β-hydroxysteroid dehydrogenase type 1 inhibitors in diabetic ob/ob mice

11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) has attracted considerable attention as a potential target for the treatment of diabetes and metabolic syndrome. Herein we report the design, synthesis and efficacy evaluation of novel amide and urea 11β-