1373260-64-0

Basic information

• Product Name: N-phenyl-4-diethylphosphoryloxy-1,2-dihydro-1-methyl-2-oxoquinoline-3-carboxamide
• Synonyms: N-phenyl-4-diethylphosphoryloxy-1,2-dihydro-1-methyl-2-oxoquinoline-3-carboxamide
• CAS NO: 1373260-64-0
• Molecular Weight: 430.397
• Mol File: 1373260-64-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-phenyl-4-diethylphosphoryloxy-1,2-dihydro-1-methyl-2-oxoquinoline-3-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-phenyl-4-diethylphosphoryloxy-1,2-dihydro-1-methyl-2-oxoquinoline-3-carboxamide(1373260-64-0)
• EPA Substance Registry System: N-phenyl-4-diethylphosphoryloxy-1,2-dihydro-1-methyl-2-oxoquinoline-3-carboxamide(1373260-64-0)

Safety Data

• Hazardous Substances Data: 1373260-64-0(Hazardous Substances Data)

Upstream product

• 1373260-65-1 N-(2,4-dimethoxybenzyl)-N-phenyl-4-diethylphosphoryloxy-1,2-dihydro-1-methyl-2-oxoquinoline-3-carboxamide 
• 1373260-61-7 N-(2,4-dimethoxybenzyl)-N-phenyl-1,2-dihydro-4-hydroxy-1-methyl-2-oxoquinoline-3-carboxamide 
• 356094-10-5 N-{[2,4-bis(methyloxy)phenyl]methyl}aniline 
• 62-53-3 aniline 

Relevant articles and documents

1,2-DIHYDRO-4-HYDROXY-2-OXO-QUINOLINE-3-CARBOXANILIDES AS AHR ACTIVATORS.

The present invention relates to compounds which are 1, 2-dihydro-4- hydroxy-2-oxo-quinoline-3-carboxanilides, their thieno-pyridone analogs, and prodrugs thereof. This invention specifically relates to such derivatives containing an N-hydrogen in the carboxanilide moiety and which exhibit modulating activity towards the aromatic hydrocarbon receptor (AhR), and, specifically, also to prodrugs thereof. The present invention also relates to use of said compounds as a medicament, and for the treatment of cancer, autoimmune disorders and other disorders with an immunological component, and a pharmaceutical composition comprising one or more of said compounds and a method of treatment.