1373273-47-2

Basic information

• Product Name: (1-(tert-butoxycarbonyl)-1H-pyrrolo[3,2-c]pyridin-2-yl)boronic acid
• CAS NO: 1373273-47-2
• Molecular Weight: 262.073
• Mol File: 1373273-47-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (1-(tert-butoxycarbonyl)-1H-pyrrolo[3,2-c]pyridin-2-yl)boronic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (1-(tert-butoxycarbonyl)-1H-pyrrolo[3,2-c]pyridin-2-yl)boronic acid(1373273-47-2)
• EPA Substance Registry System: (1-(tert-butoxycarbonyl)-1H-pyrrolo[3,2-c]pyridin-2-yl)boronic acid(1373273-47-2)

Safety Data

• Hazardous Substances Data: 1373273-47-2(Hazardous Substances Data)

Usage

General Description

(1-(tert-butoxycarbonyl)-1H-pyrrolo[3,2-c]pyridin-2-yl)boronic acid, also known as Boc-pyridylboronic acid, is a boronic acid derivative with the molecular formula C14H17BClNO3. It is a white to off-white solid that is commonly used in organic synthesis, particularly in the formation of carbon-carbon and carbon-heteroatom bonds. (1-(tert-butoxycarbonyl)-1H-pyrrolo[3,2-c]pyridin-2-yl)boronic acid is often employed as a reagent in Suzuki-Miyaura cross-coupling reactions, which are important in the synthesis of pharmaceuticals, agrochemicals, and materials. Boc-pyridylboronic acid has also shown potential in the development of new drug molecules and has been the subject of research in medicinal chemistry and drug discovery. Additionally, it has been utilized in the construction of complex molecular structures and as a building block in the preparation of diverse organic compounds.

Upstream product

• 271-34-1 5-azaindole 
• 24424-99-5 di-tert-butyl dicarbonate 
• 5419-55-6 Triisopropyl borate 
• 148760-75-2 tert-butyl 1H-pyrrolo[3,2-c]pyridine-1-carboxylate 

Relevant articles and documents

3-(1H-PYRROLO[3,2-C]PYRIDIN-2-YL)-1H-PYRAZOLO[3,4-B]PYRIDINES AND THERAPEUTIC USES THEREOF

7-Azaindazole compounds for treating various diseases and pathologies are disclosed. More particularly, the present disclosure concerns the use of a 7-azaindazole compound or analogs thereof, in the treatment of disorders characterized by the activation of Wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis, fibrotic disorders, bone or cartilage diseases, and osteoarthritis), the modulation of cellular events mediated by Wnt pathway signaling, as well as genetic diseases and neurological conditions/disorders/diseases due to mutations or dysregulation of the Wnt pathway and/or of one or more of Wnt signaling components. Also provided are methods for treating Wnt-related disease states.

3-(1H-PYRROLO[3,2-C]PYRIDIN-2-YL)-1H-INDAZOLES AND THERAPEUTIC USES THEREOF

Indazole compounds for treating various diseases and pathologies are disclosed. More particularly, the present disclosure concerns the use of an indazole compound or analogs thereof, in the treatment of disorders characterized by the activation of Wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis, fibrotic disorders, bone or cartilage diseases, and osteoarthritis), the modulation of cellular events mediated by Wnt pathway signaling, as well as genetic diseases and neurological conditions/disorders/diseases due to mutations or dysregulation of the Wnt pathway and/or of one or more of Wnt signaling components. Also provided are methods for treating Wnt-related disease states.