137330-13-3 Usage
Uses
Different sources of media describe the Uses of 137330-13-3 differently. You can refer to the following data:
1. Tilmicosin phosphate is a salt of the semi-synthetic antibiotic derivative of desmycosin (tylosin B), a minor co-metabolite of tylosin, prepared by mixing the active tilmicosin with phosphoric acid to provide improved solubility and enhanced pharmacokinetics. Tilmicosin is a broad sepctrum antibiotic, providing good protection against Pasteurella in livestock.
2. Tilmicosin Phosphate Salt is the phosphate salt of the semi-synthetic antibiotic derivative. It can be used in biological study and pharmacological activity of bactericidal effects of various concentrations of enrofloxacin, florfenicol, tilmicosin phosphate, and tulathromycin on clinical isolates of Mannheimia haemolytica from cattle.
Check Digit Verification of cas no
The CAS Registry Mumber 137330-13-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,7,3,3 and 0 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 137330-13:
(8*1)+(7*3)+(6*7)+(5*3)+(4*3)+(3*0)+(2*1)+(1*3)=103
103 % 10 = 3
So 137330-13-3 is a valid CAS Registry Number.
InChI:InChI=1/C20H22N2O4/c1-12-5-6-15-10-16-9-14(7-8-17(16)26-19(15)21-12)13(2)20(24)25-11-18(23)22(3)4/h5-9,13H,10-11H2,1-4H3/t13-/m1/s1
137330-13-3Relevant articles and documents
Tilmicosin phosphate preparation method
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Paragraph 0046; 0047; 0048, (2016/12/16)
The invention relates to a tilmicosin phosphate preparation method. The preparation method comprises that through hydrolysis under acidic conditions, alkalization extraction, amination, phosphorylation with phosphoric pentoxide and a small amount of water, full stirring salification, centrifugation separation after solid precipitation and vacuum drying, tilmicosin phosphate is prepared from tylosin tartrate as a raw material. According to the preparation method, phosphoric pentoxide and a small amount of water are directly added into an amination liquid, the mixture undergoes a phosphorylation reaction and tilmicosin phosphate is precipitated from the organic solvent. The preparation method has a final mole yield of 95% or more and a simple process route, can be operated easily, is free of spray drying production equipment, has a low production cost and realizes recycle of an organic solvent.
