1373309-01-3

Upstream product

• 23661-29-2 phenyl 2,3,4,6-tetra-O-acetyl-1-seleno-β-D-glucopyranoside 
• 572-09-8 2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl bromide 

Downstream Products

• 1373309-05-7 2,3,4,6-tetra-O-p-methoxybenzyl-1-tert-butyI-dimethylsilyl-5-hydroxy-D-gIucitol 
• 1373309-02-4 2,3,4,6-tetra-O-p-methoxybenzyl-1,5-di-O-methanesulfonyl-D-gIucitol 
• 1373309-07-9 2,3,4,6-tetra-O-p-methoxybenzyl-1,5-dihydroxy-L-iditol 
• 1373309-08-0 2,3,4,6-tetra-O-p-methoxybenzyl-1,5-di-O-methanesulfonyl-L-iditol 
• 1373309-09-1 2,3,4,6-tetra-O-p-methoxybenzyl-1,5-anhydro-5-seleno-D-glucitol 

Relevant academic research and scientific papers

SELENO-COMPOUNDS AND THERAPEUTIC USES THEREOF

The present invention relates to compounds and compositions useful as antioxidants and in particular to selenium containing compounds of formula (I): wherein n is 1, 2, or 3; m is 2, 3, 4, or 5; and each R] is independently -(optionally substituted C 1 -C3 alkylene) p-OH, where p is 0 or 1, or a salt thereof. The invention also relates to the use of these seleno-compounds in the treatment of diseases or conditions associated with increased levels of oxidants produced by myeloperoxidase (MPO), such as for instance, atherosclerosis.