1373358-11-2

Upstream product

• 1207681-10-4 methyl 2-(phenyl(tosylimino)methyl)acrylate 
• 1207681-12-6 methyl 2-((4-methoxyphenyl)(tosylimino)methyl)acrylate 
• 1373358-08-7 (R)-methyl 1,6-dioxo-8-phenyl-7-tosyl-7-azaspiro[4.5]dec-8-ene-9-carboxylate 
• 1373358-10-1 (R)-1,6-dioxo-8-phenyl-7-tosyl-7-azaspiro[4.5]dec-8-ene-9-carbaldehyde 
• 1826-67-1 vinyl magnesium bromide 
• 1373358-12-3 C₂₃H₂₃NO₅S 
• 1373357-80-2 (5S,6S)-methyl 6-hydroxy-1-oxo-8-phenyl-7-tosyl-7-azaspiro[4.5]dec-8-ene-9-carboxylate 
• 1373357-77-7 C₆H₇O₂^(1-)*K⁽¹⁺⁾ 

Relevant academic research and scientific papers

Bifunctional organocatalytic strategy for inverse-electron-demand diels-alder reactions: Highly efficient in-situ substrate generation and activation to construct azaspirocyclic skeletons

Skeletons in the flask: The first highly enantioselective organocatalytic version of the title reaction using an in-situ substrate generation/activation catalytic mode is described (see scheme). The reaction provides an efficient enantioselective construction of functionalized azaspirocyclic skeletons. The in-situ generation of the enolate provides a new way in which to use this important nucleophile in organic synthesis. Copyright