137339-65-2 Usage
General Description
The chemical composition "SER-PHE-LEU-LEU-ARG-ASN-PRO-ASN-ASP-LYS-TYR-GLU-PRO-PHE" is a sequence of amino acids that forms a peptide. This peptide is made up of 13 amino acids, including serine, phenylalanine, leucine, arginine, asparagine, proline, aspartic acid, lysine, tyrosine, and glutamic acid. These amino acids are arranged in a specific order, with each one contributing to the overall structure and function of the peptide. Peptides like these can have various biological functions, including signaling within the body, serving as neurotransmitters, or acting as hormones. Additionally, they can also be used in the development of pharmaceutical drugs and research.
Check Digit Verification of cas no
The CAS Registry Mumber 137339-65-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,7,3,3 and 9 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 137339-65:
(8*1)+(7*3)+(6*7)+(5*3)+(4*3)+(3*9)+(2*6)+(1*5)=142
142 % 10 = 2
So 137339-65-2 is a valid CAS Registry Number.
InChI:InChI=1/C81H118N20O23/c1-43(2)34-53(93-71(114)54(35-44(3)4)94-73(116)55(92-67(110)49(83)42-102)36-45-16-7-5-8-17-45)70(113)90-51(21-13-31-88-81(86)87)69(112)98-59(40-64(85)105)79(122)101-33-15-22-61(101)76(119)97-57(39-63(84)104)74(117)96-58(41-66(108)109)75(118)89-50(20-11-12-30-82)68(111)95-56(37-47-24-26-48(103)27-25-47)72(115)91-52(28-29-65(106)107)78(121)100-32-14-23-62(100)77(120)99-60(80(123)124)38-46-18-9-6-10-19-46/h5-10,16-19,24-27,43-44,49-62,102-103H,11-15,20-23,28-42,82-83H2,1-4H3,(H2,84,104)(H2,85,105)(H,89,118)(H,90,113)(H,91,115)(H,92,110)(H,93,114)(H,94,116)(H,95,111)(H,96,117)(H,97,119)(H,98,112)(H,99,120)(H,106,107)(H,108,109)(H,123,124)(H4,86,87,88)/t49-,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,62-/m0/s1
137339-65-2Relevant articles and documents
Development of a Potent Thrombin Receptor Ligand
Feng, Dong-Mei,Veber, Daniel F.,Connolly, Thomas M.,Condra, Cindra,Tang, Mei-Jy,Nutt, Ruth F.
, p. 4125 - 4130 (1995)
The N-terminal thrombin receptor peptide H-Ser-Phe-Leu-Leu-Arg-Asn-Pro-Asn-Asp-Lys-Tyr-Glu-Pro-Phe-OH (1) fully activates the thrombin receptor with an EC50 of 10 μM.Structural features in the tetradecapeptide which are responsible for receptor activation have been elucidated.Agonist potency has been enhanced 1000-fold with the design of the shortened peptide H-Ala-Phe(p-F)-Arg-Cha-HArg-Tyr-NH2 (56).This analog exhibits an EC50 of 0,01 μM and is the most potent agonist for receptor activation reported to date.The monoiodinated derivative H-Ala-Phe(p-F)-Arg-Cha-HArg-Tyr(3-I)-NH2 (59) exhibits an EC50 of 0.03 μM, a level sufficient for development of a radioligand.
