1373392-21-2Relevant academic research and scientific papers
A novel sugar based intramolecular Ugi 3CC for the N-alkyl-3-oxo-4-aryl- octahydrofuro[2,3-f][1,4]oxazepine-5-carboxamides
Reddy, B.V. Subba,Majumder, Nilanjan,Prabhakar Rao,Sridhar
, p. 2273 - 2276 (2012)
An intramolecular Ugi reaction of 3-carboxy tethered sugar aldehyde with aryl amines and isocyanides has been accomplished to produce a novel class of carbohydrate derivatives, 3-oxo-4-aryl-octahydrofuro[2,3-f][1,4]oxazepine-5- carboxamides in good yields. The stereochemistry of the products was assigned by NMR studies. This is the first report on intramolecular Ugi reaction of 3-carboxy tethered sugar aldehyde, aryl amine, and isonitrile.
