Cas 1373397-01-3,benzyl (2-amino-9-((2R,3R,4R,5R)-3,4-bis(((benzyloxy)carbonyl)oxy)-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)carbamate

1373397-01-3

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Basic information

Product Name: benzyl (2-amino-9-((2R,3R,4R,5R)-3,4-bis(((benzyloxy)carbonyl)oxy)-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)carbamate
Synonyms: benzyl (2-amino-9-((2R,3R,4R,5R)-3,4-bis(((benzyloxy)carbonyl)oxy)-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)carbamate
CAS NO:1373397-01-3
Molecular Formula:
Molecular Weight: 684.662
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: benzyl (2-amino-9-((2R,3R,4R,5R)-3,4-bis(((benzyloxy)carbonyl)oxy)-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)carbamate(CAS DataBase Reference)
NIST Chemistry Reference: benzyl (2-amino-9-((2R,3R,4R,5R)-3,4-bis(((benzyloxy)carbonyl)oxy)-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)carbamate(1373397-01-3)
EPA Substance Registry System: benzyl (2-amino-9-((2R,3R,4R,5R)-3,4-bis(((benzyloxy)carbonyl)oxy)-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)carbamate(1373397-01-3)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 1373397-01-3(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 1373397-01-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,7,3,3,9 and 7 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1373397-01:
(9*1)+(8*3)+(7*7)+(6*3)+(5*3)+(4*9)+(3*7)+(2*0)+(1*1)=173
173 % 10 = 3
So 1373397-01-3 is a valid CAS Registry Number.

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1373397-01-3Relevant academic research and scientific papers

Efficient synthesis of exo-N-carbamoyl nucleosides: Application to the synthesis of phosphoramidate prodrugs

Cho, Jong Hyun,Coats, Steven J.,Schinazi, Raymond F.

, p. 2488 - 2491 (2012)

An efficient protection protocol for the 6-exo-amino group of purine nucleosides with various chloroformates was developed utilizing N-methylimidazole (NMI). The reaction of an exo-N6-group of adenosine analogue 1 with alkyl/and aryl chloroformates under optimized conditions provided the N6-carbamoyl adenosines (2a-j) in good to excellent yields. The reaction of N6-Cbz-protected nucleosides (5a-c) with phenyl phosphoryl chloride (7) using t-BuMgCl followed by catalytic hydrogenation afforded the corresponding phosphoramidate pronucleotides (8a-c) in excellent yield.

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