1373398-91-4Relevant academic research and scientific papers
Thiacycloalkynes for copper-free click chemistry
De Almeida, Gabriela,Sletten, Ellen M.,Nakamura, Hitomi,Palaniappan, Krishnan K.,Bertozzi, Carolyn R.
supporting information; experimental part, p. 2443 - 2447 (2012/04/23)
The heteroatom helps! The introduction of an endocyclic sulfur atom enables fine-tuning of the reactivity and stability of thiacycloalkynes for copper-free click chemistry. The stabilizing effect of the endocyclic sulfur atom allows the use of highly activated seven-membered rings as reagents for bioorthogonal copper-free click chemistry. Copyright
