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Upstream product

• 104-94-9 4-methoxy-aniline 
• 504-02-9 1,3-cylohexanedione 
• 1220515-82-1 2-iodo-3-[(4-methoxyphenyl)(phenyl)amino]cyclohex-2-enone 
• 56964-05-7 2-phenylcyclohexane-1,3-dione 
• 1373402-40-4 3-(4-methoxyphenylamino)-2-phenylcyclohex-2-enone 

Relevant academic research and scientific papers

Synthesis of N-substituted carbazolones from α-iodo enaminones via Pd(0)-catalyzed intramolecular coupling under microwave irradiation

A variety of N-aryl and N-alkyl carbazolones were conveniently achieved in good to high yields via Pd2(dba)3-mediated intramolecular coupling of N-substituted α-iodo enaminones under microwave irradiation. The Pd(0)-catalyzed cyclization was found to proceed favorably with the more electron-deficient phenyl ring during the reactions involving unsymmetrical N,N-diaryl α-iodo enaminones. This unique property enables the construction of carbazolone skeleton containing nitro substituted benzenoid ring.

Synthesis of carbazolones and 3-acetylindoles via oxidative C-N bond formation through PIFA-mediated annulation of 2-aryl enaminones

A series of carbazolone derivatives and 3-acetylindoles have been achieved via PIFA-mediated intramolecular cyclization of 2-aryl enaminones. This process allows the N-moiety on the side-chain to be annulated to the benzene ring via the metal-free oxidative aromatic C-N bond formation.