1373403-47-4Relevant academic research and scientific papers
Enantiodivergent and γ-selective asymmetric allylic amination
Wang, Jianmin,Chen, Jie,Kee, Choon Wee,Tan, Choon-Hong
supporting information; experimental part, p. 2382 - 2386 (2012/05/19)
Double agent: The title reaction using the guanidine catalyst 1 can deliver both enantiomers of the product with excellent enantioselectivity by judicious choice of the double bond geometry of the the β,γ-unsaturated carbonyl compound. Computational studies reveal the possible origin of the inversed enantioselectivity, and the potential for enantiodivergent synthesis chiral amine-containing substrates is attractive. Copyright
