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CAS

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1373417-03-8

1-{1-[2-(difluoromethoxy)-4-nitrophenyl]piperidin-4-yl}-4-methylpiperazine is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1373417-03-8 Structure

  • Basic information

    1. Product Name: 1-{1-[2-(difluoromethoxy)-4-nitrophenyl]piperidin-4-yl}-4-methylpiperazine
    2. Synonyms: 1-{1-[2-(difluoromethoxy)-4-nitrophenyl]piperidin-4-yl}-4-methylpiperazine
    3. CAS NO:1373417-03-8
    4. Molecular Formula:
    5. Molecular Weight: 370.399
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1373417-03-8.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 502.8±50.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: 1.272±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 1-{1-[2-(difluoromethoxy)-4-nitrophenyl]piperidin-4-yl}-4-methylpiperazine(CAS DataBase Reference)
    10. NIST Chemistry Reference: 1-{1-[2-(difluoromethoxy)-4-nitrophenyl]piperidin-4-yl}-4-methylpiperazine(1373417-03-8)
    11. EPA Substance Registry System: 1-{1-[2-(difluoromethoxy)-4-nitrophenyl]piperidin-4-yl}-4-methylpiperazine(1373417-03-8)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1373417-03-8(Hazardous Substances Data)

1373417-03-8 Usage

Chemical structure

A complex compound with a piperidine and piperazine structure, along with difluoromethoxy and nitrophenyl groups.

Molecular weight

414.404 g/mol

Potential applications

Pharmaceutical or research applications, such as a drug candidate or a chemical probe for studying biological processes.

Specific properties and functions

Depend on the context and purpose for which it is being used.

Check Digit Verification of cas no

The CAS Registry Mumber 1373417-03-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,7,3,4,1 and 7 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1373417-03:
(9*1)+(8*3)+(7*7)+(6*3)+(5*4)+(4*1)+(3*7)+(2*0)+(1*3)=148
148 % 10 = 8
So 1373417-03-8 is a valid CAS Registry Number.

1373417-03-8Relevant articles and documents

NITROGEN-CONTAINING AROMATIC HETEROCYCLIC COMPOUND

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Paragraph 0283, (2014/05/25)

Provided is a compound useful as a prophylactic and/or therapeutic agent for bladder cancer. As a result of studies on compounds having FGFR inhibitory action, the present inventors have found that the nitrogen-containing aromatic heterocyclic compounds of the present invention have inhibitory action on FGFR1, FGFR2, and/or FGFR3, particularly, mutant FGFR3, and thus, the present invention has been accomplished. The nitrogen-containing aromatic heterocyclic compound of the present invention can be used as a therapeutic agent for various cancers related to FGFR1, FGFR2, and/or FGFR3, such as lung cancer and hormone therapy-resistant breast cancer, stomach cancer, triple negative breast cancer, endometrial cancer, bladder cancer, and glioblastoma, particularly as a prophylactic and/or therapeutic agent for mutant FGFR3-positive bladder cancer.

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