1373427-97-4

Basic information

• Product Name: methyl 5-(2-bromoacetyl)-2-hexyloxybenzoate
• Synonyms: methyl 5-(2-bromoacetyl)-2-hexyloxybenzoate
• CAS NO: 1373427-97-4
• Molecular Weight: 357.244
• Mol File: 1373427-97-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl 5-(2-bromoacetyl)-2-hexyloxybenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 5-(2-bromoacetyl)-2-hexyloxybenzoate(1373427-97-4)
• EPA Substance Registry System: methyl 5-(2-bromoacetyl)-2-hexyloxybenzoate(1373427-97-4)

Safety Data

• Hazardous Substances Data: 1373427-97-4(Hazardous Substances Data)

Upstream product

• 1373427-91-8 methyl 5-acetyl-2-hexyloxybenzoate 
• 16475-90-4 estere metilico dell'acido 5-acetilsalicilico 

Downstream Products

• 1373428-15-9 5-(2-(4-(2,3,4-trimethoxybenzyl)piperazin-1-yl)acetyl)-2-(hexyloxy)benzoic acid 
• 1373428-24-0 5-(2-(4-(2,3,4-trimethoxybenzyl)piperazin-1-yl)acetyl)-2-(hexyloxy)benzoyl guanidine 
• 1373428-06-8 methyl 5-(2-(4-(2,3,4-trimethoxybenzyl)piperazin-1-yl)acetyl)-2-(hexyloxy)benzoate 

Relevant articles and documents

Synthesis and bioactivity of substituted benzoylguanidine derivatives as potent Na+/H+ exchanger inhibitors

A novel series of substituted benzoylguanidine derivatives were designed and synthesized in order to evaluate their NHE1 inhibitory activity. Most of them were found to inhibit NHE1-mediated platelet swelling in a concentration-dependent manner, and eight compounds showed more potent NHE1 inhibitory activity than Cariporide. Compound 6f with an IC50 value of 1.08 × 10-10 molmiddot;L-1, was 39 times more potent than lead compound CPU-X-050420 in vitro tests. A novel series of 5-(2-(4-(2,3,4-trimethoxybenzyl)piperazin-1-yl)acetyl)benzoylguanidine derivatives 6a-6i have been synthesized and screened for their NHE1 inhibitory activity. Copyright