1373499-54-7

Upstream product

• 1373500-28-7 3-(2-chlorophenyl)-4-(2-methylphenyl)-5-(2-methyl-4-methoxyphenyl)isoxazole 
• 1373500-27-6 C₁₅H₁₄ClNO 
• 1184640-29-6 2-(2-methylphenyl)(2-chlorophenyl)ethanone 
• 2142-68-9 1-(2-chlorophenyl)ethanone 
• 95-46-5 2-methylphenyl bromide 

Relevant academic research and scientific papers

ISOXAZOLE DERIVATIVES USED AS OESTROGEN MODULATORS

The present invention relates to a substituted isoxazole derivative according to formula (I), wherein the variables are defined as in the specification, or to a pharmaceutically acceptable salt, solvate or prodrug thereof. The present invention also relates to a pharmaceutical composition comprising said substituted isoxazole derivatives and to their use as a contraceptive or in therapy, for instance in the treatment or prevention of estrogen-receptor mediated disorders or estrogen-receptor related physiological conditions such as climacteric disorders and osteoporosis.