1373648-52-2

Upstream product

• 1373648-49-7 3-(3-(dimethylamino)acryloyl)-4-phenyl-1-oxaspiro[4,5]dec-3-en-2-one 
• 1373648-45-3 3-acetyl-5,5-pentamethylen-4-phenylfuran-2(5H)-one 

Relevant academic research and scientific papers

Synthesis of some heterocyclic compounds from enamines of 3-acetylfuran-2(5 H)-ones

The interaction of different 3-acetylfuran-2(5H)-ones (1, 4) with dimethylformamide dimethyl acetal (DMF/DMA) has been investigated, and the condensed furopyridine system 3 was obtained. By means of interaction of compounds 4 and DMF/DMA via the 3-acetylfuran-2(5H)-one enamines, the heterocyclic substituted furanones are obtained. The condensation of 3-acetyl-4,5,5-trimethylfuran-2(5H)-one (1a) with veratraldehyde was realized. Through the interaction of 1a with malononitrile and further intramolecular condensation of the product, 6-amino-dihydroisobenzofuran-5-carbonitrile was also synthesized.