1373760-97-4Relevant academic research and scientific papers
Highly efficient and simple catalytic system for the N-arylation of some hindered aza-heterocycles in water
Mukhopadhyay, Chhanda,Tapaswi, Pradip Kumar
experimental part, p. 2217 - 2228 (2012/06/18)
A highly efficient and simple protocol for the N-arylation of some hindered aza-heterocycles in water has been developed with readily available basic copper carbonate as the catalyst using bis(3,5-dimethyl-1H-pyrazol-1-yl)methane as ligand. This mild catalytic system possesses excellent tolerance for a large variety of functional groups. A total of 11 previously unknown coupling products have been synthesized by this methodology.
