137379-61-4

Basic information

• Product Name: (4-FLUORO-BENZYL)-ISOPROPYL-AMINE
• Synonyms: CHEMBRDG-BB 5402692;(4-FLUORO-BENZYL)-ISOPROPYL-AMINE;N-(4-FLUOROBENZYL)-N-ISOPROPYLAMINE;N-(4-FLUOROPHENYLMETHYL)ISOPROPYLAMINE;UKRORGSYN-BB BBV-038986;(4-fluorobenzyl)isopropylamine(SALTDATA: HCl);4-Fluoro-N-isopropylbenzylaMine, 97%
• CAS NO: 137379-61-4
• Molecular Formula: C10H14FN
• Molecular Weight: 167.22
• Mol File: 137379-61-4.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 211.6°C at 760 mmHg
• Flash Point: 81.8°C
• Appearance: /
• Density: 0.991g/cm³
• Vapor Pressure: 0.181mmHg at 25°C
• Refractive Index: 1.488
• PKA: 9.74±0.19(Predicted)
• CAS DataBase Reference: (4-FLUORO-BENZYL)-ISOPROPYL-AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: (4-FLUORO-BENZYL)-ISOPROPYL-AMINE(137379-61-4)
• EPA Substance Registry System: (4-FLUORO-BENZYL)-ISOPROPYL-AMINE(137379-61-4)

Safety Data

• Hazardous Substances Data: 137379-61-4(Hazardous Substances Data)

Usage

General Description

The chemical compound "(4-FLUORO-BENZYL)-ISOPROPYL-AMINE" is a compound consisting of a fluorinated benzyl group attached to an isopropylamine group. It is an amine derivative with a benzyl group substituted with a fluorine atom and an isopropyl group. (4-FLUORO-BENZYL)-ISOPROPYL-AMINE may have applications in pharmaceuticals, as a reagent in chemical synthesis, or in research and development. It should be handled and used with caution, following appropriate safety protocols, due to its potential health and safety hazards.

InChI:InChI=1/C10H14FN/c1-8(2)12-7-9-3-5-10(11)6-4-9/h3-6,8,12H,7H2,1-2H3

Upstream product

• 459-57-4 4-fluorobenzaldehyde 
• 75-31-0 isopropylamine 
• 459-23-4 4-fluorobenzaldoxime 
• 67-64-1 acetone 

Relevant articles and documents

INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE AND METHODS OF THEIR USE

The present invention provides compounds of formula (I): wherein all of the variables are as defined herein. These compounds are inhibitors of indoleamine 2,3-dioxygenase (IDO), which may be used as medicaments for the treatment of proliferative disorders, such as cancer, viral infections and/or autoimmune diseases.

Photocatalyzed cascade Meerwein addition/cyclization of: N -benzylacrylamides toward azaspirocycles

A visible-light-induced cascade Meerwein addition/cyclization of alkenes involving C-F bond cleavage was developed. This method offers a rapid access to azaspirocyclic cyclohexadienones from N-benzylacrylamides via C-F bond cleavage applying H2O as an external oxygen source, allowing for the incorporation of various aromatic moieties originating from aryldiazonium salts.