1373887-69-4

Basic information

• Product Name: C₁₅H₁₀Cl₂N₂O₂
• CAS NO: 1373887-69-4
• Molecular Weight: 321.163
• Mol File: 1373887-69-4.mol

Chemical Properties

• CAS DataBase Reference: C₁₅H₁₀Cl₂N₂O₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₅H₁₀Cl₂N₂O₂(1373887-69-4)
• EPA Substance Registry System: C₁₅H₁₀Cl₂N₂O₂(1373887-69-4)

Safety Data

• Hazardous Substances Data: 1373887-69-4(Hazardous Substances Data)

Upstream product

• 837-58-1 2-amino-4'-chloro-5-chlorobenzophenone 
• 298-12-4 Glyoxilic acid 

Downstream Products

• 1373887-34-3 6-chloro-N-isobutyl-N-methyl-4-phenylquinazoline-2-carboxamide 
• 1373887-48-9 N-sec-butyl-6-chloro-4-(4-chlorophenyl)quinazoline-2-carboxamide 
• 1373887-49-0 N-sec-butyl-6-chloro-4-(4-chlorophenyl)-N-methylquinazoline-2-carboxamide 
• 1373887-50-3 6-chloro-4-(4-chlorophenyl)-N-isobutyl-N-methylquinazoline-2-carboxamide 
• 1373887-51-4 6-chloro-4-(4-chlorophenyl)-N-isopropyl-N-methylquinazoline-2-carboxamide 
• 1373887-63-8 6-chloro-4-(4-chlorophenyl)-N-isobutylquinazoline-2-carboxamide 
• 1373887-66-1 6-chloro-4-(4-chlorophenyl)quinazoline-2-carboxylic acid 
• 1373887-25-2 azepan-1-yl[6-chloro-4-(4-chlorophenyl)quinazolin-2-yl]methanone 
• 1373887-24-1 [6-chloro-4-(4-chlorophenyl)quinazolin-2-yl](piperidin-1-yl)methanone 
• 1373887-23-0 [6-chloro-4-(4-chlorophenyl)quinazolin-2-yl](pyrrolidin-1-yl)methanone 
• 1373887-22-9 6-chloro-4-(4-chlorophenyl)-N,N-dihexylquinazoline-2-carboxamide 

Relevant articles and documents

Synthesis and biological evaluation of 4-phenylquinazoline-2-carboxamides designed as a novel class of potent ligands of the translocator protein

A series of novel 4-phenylquinazoline-2-carboxamides (1-58) were designed as aza-isosters of PK11195, the well-known 18 kDa translocator protein (TSPO) reference ligand, and synthesized by means of a very simple and efficient procedure. A number of these derivatives bind to the TSPO with Ki values in the nanomolar/subnanomolar range, show selectivity toward the central benzodiazepine receptor (BzR) and exhibit structure-affinity relationships consistent with a previously published pharmacophore/topological model of ligand-TSPO interaction.