1373889-46-3

Basic information

• Product Name: C₁₉H₁₈ClN₃O
• Synonyms: C₁₉H₁₈ClN₃O
• CAS NO: 1373889-46-3
• Molecular Weight: 339.824
• Mol File: 1373889-46-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₉H₁₈ClN₃O(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₉H₁₈ClN₃O(1373889-46-3)
• EPA Substance Registry System: C₁₉H₁₈ClN₃O(1373889-46-3)

Safety Data

• Hazardous Substances Data: 1373889-46-3(Hazardous Substances Data)

Upstream product

• 59236-37-2 2-amino-4-chlorobenzaldehyde 
• 133550-33-1 N-(3-phenyl-n-propyl)-cyanoacetamide 
• 2038-57-5 3-Phenylpropan-1-amine 
• 5551-11-1 4-Chloro-2-nitrobenzaldehyde 

Relevant articles and documents

Cyanoacetamides (IV): Versatile one-pot route to 2-quinoline-3-carboxamides

Cyanoacetic acid derivatives are the starting materials for a plethora of multicomponent reaction (MCR) scaffolds. Herein, we describe scope of a valuable general protocol for the synthesis of arrays of 2-aminoquinoline-3-carboxamides from cyanoacetamides and 2-aminobenzaldehydes or heterocyclic derivatives via a Friedlaender reaction variation. In many cases, the reactions involve a very convenient work up by simple precipitation and filtration. More than 40 new products are described. We foresee our protocol and the resulting derivatives becoming very valuable to greatly expanding the scaffold space of cyanoacetamide derivatives.