1373929-08-8

Basic information

• Product Name: methyl (2R,3R)-3-hydroxy-2-(hydroxymethyl)-3-(benzyloxymethyl)-5-oxopyrrolidine-2-carboxylate
• CAS NO: 1373929-08-8
• Molecular Weight: 309.319
• Mol File: 1373929-08-8.mol

Chemical Properties

• CAS DataBase Reference: methyl (2R,3R)-3-hydroxy-2-(hydroxymethyl)-3-(benzyloxymethyl)-5-oxopyrrolidine-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (2R,3R)-3-hydroxy-2-(hydroxymethyl)-3-(benzyloxymethyl)-5-oxopyrrolidine-2-carboxylate(1373929-08-8)
• EPA Substance Registry System: methyl (2R,3R)-3-hydroxy-2-(hydroxymethyl)-3-(benzyloxymethyl)-5-oxopyrrolidine-2-carboxylate(1373929-08-8)

Safety Data

• Hazardous Substances Data: 1373929-08-8(Hazardous Substances Data)

Upstream product

• 67354-37-4 4-(benzyloxy)-3-oxobutanoic acid 
• 1373929-04-4 (2R,5R,6R)-1-aza-2-(tert-butyl)-6-hydroxy-6-(benzyloxymethyl)-5-methoxycarbonyl-3-oxa-8-oxobicyclo[3.3.0]octane 
• 1373928-98-3 methyl (2R,4S)-3-(4-benzyloxy-3-oxobutanoyl)-2-t-butyl-oxazolidine-4-carboxylate 
• 61795-51-5 benzyl 4-(benzyloxy)-3-oxobutanoate 

Relevant articles and documents

Biomimetic synthesis, antibacterial activity and structure-activity properties of the pyroglutamate core of oxazolomycin

Biomimetic intramolecular aldol reactions on oxazolidine templates derived from serine may be used to generate densely functionalised pyroglutamates, which are simpler mimics of the right hand side of oxazolomycin. Some of the compounds from this sequence exhibit in vivo activity against S. aureus and E. coli, suggesting that pyroglutamate scaffolds may be useful templates for the development of novel antibacterials, and cheminformatic analysis has been used to provide some structure-activity data.