1373935-55-7Relevant academic research and scientific papers
Facile synthesis of nonsymmetrical heteroaryl-substituted triarylmethanes: Via the FeCl3·6H2O-catalyzed two-step Friedel-Crafts-type reaction
Ruengsangtongkul,Taprasert,Sirion,Jaratjaroonphong
, p. 8493 - 8502 (2016/09/28)
The FeCl3·6H2O-catalyzed three-component aza-Friedel-Crafts reaction of aromatic/heteroaromatic compounds, aromatic aldehydes and tert-butyl carbamate was reported. The subsequent Friedel-Crafts-type alkylation of the resulting tert-
Bi(OTf)3-Catalyzed One-Step Catalytic Synthesis of N-Boc or N-Cbz Protected α-Branched Amines
Jaratjaroonphong, Jaray,Tuengpanya, Surisa,Ruengsangtongkul, Sureeporn
, p. 559 - 567 (2015/08/11)
In this paper, N-Boc and N-Cbz protected α-branched amines are synthesized directly from commercially available aromatic/heteroaromatic compounds, aldehydes, and tert-butyl or benzyl carbamate bearing a variety of substituents. Bismuth(III) triflate is found to be a highly effective catalyst for this one-pot, three-component coupling reaction. In addition, the use of mild reaction conditions, low catalytic loading, easy removal of the N-protective group, and one-step synthesis under "open-flask" are advantages of the present procedure.
Iodine-catalyzed, one-pot, three-component aza-Friedel-Crafts reaction of electron-rich arenes with aldehyde/carbamate combinations
Jaratjaroonphong, Jaray,Krajangsri, Suppachai,Reutrakul, Vichai
experimental part, p. 2476 - 2479 (2012/06/01)
Iodine is shown to be an efficient catalyst for a one-step, three-component aza-Friedel-Crafts reaction of activated arenes or heteroarenes with benzyl or tert-butyl carbamates in combination with a wide variety of aldehydes in toluene under 'open-flask'
