1373998-94-7

Basic information

• Product Name: α,α'-bis(2-hydroxy-3-bromophenylidene)ketone
• Synonyms: α,α'-bis(2-hydroxy-3-bromophenylidene)ketone
• CAS NO: 1373998-94-7
• Molecular Weight: 464.153
• Mol File: 1373998-94-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: α,α'-bis(2-hydroxy-3-bromophenylidene)ketone(CAS DataBase Reference)
• NIST Chemistry Reference: α,α'-bis(2-hydroxy-3-bromophenylidene)ketone(1373998-94-7)
• EPA Substance Registry System: α,α'-bis(2-hydroxy-3-bromophenylidene)ketone(1373998-94-7)

Safety Data

• Hazardous Substances Data: 1373998-94-7(Hazardous Substances Data)

Upstream product

• 1829-34-1 2-hydroxy-3-bromobenzaldehyde 
• 108-94-1 cyclohexanone 

Downstream Products

• 1429939-32-1 (5aR,8aR)-1,13-dis(di-p-tolylphosphanyl)-5a,6,7,8,8a,9-hexahydro-5H-chromeno[3,2-d]xanthene 
• 1429939-31-0 C₅₂H₅₄O₂P₂ 

Relevant articles and documents

A chiral α - methylene β - lactam compound and its preparation method and application

Disclosed are a chiral alpha-methylene-beta-lactam compound and a preparation method and an application thereof. An asymmetric allyl amination reaction of catalyzing a class of Morita-Baylis-Hillman adducts by using a complex formed by a chiral phosphine

PROCESS FOR SYNTHESIS OF EZETIMIBE AND INTERMEDIATES USED IN SAID PROCESS

A process for the production of ezetimibe and intermediates used in said process are disclosed. A kind of Morita-Baylis-Hillman adduct can be altered to chiral carboxylic acid derivatives of β-arylamino α-methylene with high activity and selectivity by means of ally lamination reaction, and the above carboxylic acid derivatives of β-arylamino α-methylene can be altered to the chiral intermediates of ezetimibe by means of simple conversion and further synthesized into the chiral drug ezetimibe. The synthesis route introduces chirality through the use of a chiral catalysis method, thereby avoiding the use of the chiral auxiliary oxazolidinone; and the route is economical and eco-friendly.