1374007-20-1

Basic information

• Product Name: N-(4-(tert-butyl)phenyl)-S-methyl-S-(4-methylphenyl)-sulfoximine
• Synonyms: N-(4-(tert-butyl)phenyl)-S-methyl-S-(4-methylphenyl)-sulfoximine
• CAS NO: 1374007-20-1
• Molecular Weight: 301.453
• Mol File: 1374007-20-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-(4-(tert-butyl)phenyl)-S-methyl-S-(4-methylphenyl)-sulfoximine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-(tert-butyl)phenyl)-S-methyl-S-(4-methylphenyl)-sulfoximine(1374007-20-1)
• EPA Substance Registry System: N-(4-(tert-butyl)phenyl)-S-methyl-S-(4-methylphenyl)-sulfoximine(1374007-20-1)

Safety Data

• Hazardous Substances Data: 1374007-20-1(Hazardous Substances Data)

Upstream product

• 84563-54-2 bis(4-tert-butylphenyl)iodonium trifluoromethanesulfonate 
• 20414-85-1 S-methyl-S-(p-tolyl)sulfoximine 
• 7598-28-9 4-tert-butylphenyltosylate 

Relevant articles and documents

Palladium-Catalyzed N-Arylation of Sulfoximines with Aryl Sulfonates

Palladium-catalyzed C-N bond coupling reaction between NH-sulfoximines and aryl halides (e.g., -Br, -I, and -Cl and pseudohalides -OTf and -ONf) was successfully achieved. Nevertheless, aryl tosylates/mesylates left much to be achieved. In this report, a general N-arylation of sulfoximines with aryl sulfonates is described. Using Pd(OAc)2/MeO-CM-phos complex, the N-aryl sulfoximine products can be obtained in good-to-excellent yields (up to 99%) with good common functional group compatibility. In addition to arene moieties, alkenyl tosylates are shown to be successful coupling partners.